Vaughan-Hirsch, John and Goodall, Benjamin and Bishopp, Anthony (2018)North, east, south, west: mapping vascular tissues ontothe Arabidopsis root. Current Opinion in Plant Biology, 41 . pp. 16-22. ISSN 1879-0356
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The analgesic efficacy of the transversus abdominis plane peripheral nerve block following abdominal tissue breast reconstruction has not been studied in a randomized controlled trial. The authors conducted a double-blind, placebo-controlled, 1:1 allocation, two-arm parallel group, superiority design, randomized controlled trial in patients undergoing microsurgical abdominally based breast reconstruction. Intraoperatively, epidural catheters were inserted under direct vision through the triangle of Petit on both sides of the abdomen into the transversus abdominis plane just before rectus fascial closure. Patients received either bupivacaine (study group) or saline (placebo group) through the catheters for 2 postoperative days. All patients received hydromorphone by means of a patient-controlled analgesic pump. The primary outcome was the difference in the parenteral opioid consumption on each postoperative day between the groups. The secondary outcome measures included the following: total in-hospital opioid; antinausea medication; pain, nausea, and sedation scores; Quality of Recovery Score; time to ambulation; and hospital stay duration. Between September of 2011 and June of 2013, 93 patients were enrolled: 49 received bupivacaine and 44 received saline. There were 11 postoperative complications (13 percent); none were related to the catheter. Primary outcomes were completed by 85 of 93 patients (91.3 percent); the mean parenteral morphine consumption was significantly reduced on postoperative day 1 in the bupivacaine group (20.720.1 mg) compared with 30.019.1 mg in the control group (p=0.02). There were no significant differences in secondary outcomes. Following abdominally based breast reconstruction, transversus abdominis plane peripheral nerve block is safe and significantly reduces morphine consumption in the early postoperative period. Therapeutic, II.
We examined lateral distributions of 134 Cs, 137 Cs, 226 Ra, and 228 Ra in the surface seawaters around the Kuril Islands and the Kamchatka Peninsula in the northwestern North Pacific Ocean during June 2014. The sampling area included three water current areas, the Oyashio Current, the current from the Okhotsk Sea, and the coastal current along the east Kamchatka Peninsula. 226 Ra and 228 Ra distributions differed along the three currents. Low levels of 134 Cs were detected in the surface waters of the Oyashio Current (0.09-0.35 mBq/L), but it was
Loibl, Sibylle, Han, Sileny N, von Minckwitz, Gunter, Bontenbal, Marijke, Ring, Alistair, Giermek, Jerzy, Fehm, Tanja, Van Calsteren, Kristel, Linn, Sabine C, Schlehe, Bettina, Gziri, Mina Mhallem, Westenend, Pieter J, Müller, Volkmar, Heyns, Liesbeth, Rack, Brigitte, Van Calster, Ben, Harbeck, Nadia, Lenhard, Miriam, Halaska, Michael J, Kaufmann, Manfred, Nekljudova, Valentina and Amant, Frederic (2012)Treatment of breast cancer during pregnancy: an observational study. Lancet Oncology, 13 (9). pp. 887-896. ISSN 1470-2045
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